Percocet tablets are primarily used to relieve moderate to severe pain. They are a combination of a narcotic and acetaminophen. Narcotic pain relievers work by binding to opioid receptors in the brain and the spinal cord, and acetaminophen decreases the formation of prostaglandins, hence, reducing pain. Some medicines may sometimes interact with this medicine though. For example, do not take this medicine if you’re taking naltrexone, or other pain medicines such as cimetidine, isoniazid, or seizure medicines such as carbamazepine, or anticholinergic medicines or antihistamines. It should also be taken with caution if you already take medicines that cause drowsiness or anxiety. This medicine could be taken with food, even though; doing so could reduce its effectiveness. Do not take tis medicine if you have had a severe reaction to codeine, hydrocodone, dihydrocodeine or oxycodone. Or this could lead to severe rash, hives, breathing difficulties or dizziness. Avoid taking this medicine with alcohol. Possible side effects of this medicine are nausea, vomiting, constipation, lightheadedness, dizziness, flushing, vision changes or mental/mood changes. Take this medicine with a serious prescription by the doctor, only as directed by him.